Iptacopan(HCl H2O)

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Selling leads
Iptacopan(HCl H2O)
Posting date : Feb 25, 2026
Membership
Free Member Scince Jul 07, 2025
FOB Price
$313.5
Min. Order Quantity
10g
Supply Abillity
Stock
Port
Ningbo
Payment Terms
T/T 100%
Package
1g,10g,20g,
Keyword :
chemical
Category
Contact
Lunar
Selling Leads Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
Jinlan
HS-CODE
-
Package & Delivery Lead Time
Package
1g,10g,20g,
Detailed Description
CAS No.：2107031-05-3 (base)
Molecular Formula：C₃₀H₃₇ClN₆O₅S₂
Molecular Weight：649.27

Characteristic

  • Appearance：White to off-white powder
  • Solubility：Slightly soluble in water, soluble in organic solvents
  • Storage：Sealed, dry, protected from light

Pharmacological Category

Oral, selective factor B inhibitor
Complement alternative pathway inhibitor

Mechanism of Action

  • Selectively inhibits factor B in the complement alternative pathway
  • Blocks C3 convertase formation & downstream complement activation
  • Reduces complement-mediated tissue injury and inflammation

Indications

  • Paroxysmal nocturnal hemoglobinuria (PNH)
  • Immune complex-mediated membranoproliferative glomerulonephritis (IC-MPGN)
  • C3 glomerulopathy (C3G)

Key Features

  • Oral, once-daily administration
  • First-in-class oral factor B inhibitor
  • Targeted inhibition of alternative pathway

Main Adverse Reactions

  • Headache
  • Diarrhea, nausea
  • Upper respiratory tract infections
  • Increased liver enzymes (transient)

Contraindications

  • Hypersensitivity to iptacopan or any excipient
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