Atrasentan HCl

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Selling leads
Atrasentan HCl
Posting date : Feb 25, 2026
Membership
Free Member Scince Jul 07, 2025
FOB Price
$314.5
Min. Order Quantity
10g
Supply Abillity
Stock
Port
Ningbo
Payment Terms
T/T 100%
Package
1g,10g,20g,
Keyword :
chemical
Category
Contact
Lunar
Selling Leads Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
Jinlan
HS-CODE
-
Package & Delivery Lead Time
Package
1g,10g,20g,
Detailed Description
CAS No.：195732-81-6
Molecular Formula：C₂₉H₃₉ClN₄O₃
Molecular Weight：527.06

Characteristic

  • Appearance：White to off-white powder
  • Solubility：Soluble in water, methanol, DMSO
  • Storage：Sealed, dry, protected from light

Pharmacological Category

Selective endothelin A receptor antagonist

Mechanism of Action

  • Selectively blocks ETA receptor
  • Inhibits endothelin‑1‑mediated vasoconstriction and renal fibrosis
  • Reduces intraglomerular pressure and proteinuria

Indications

  • Primary research and clinical development for:
    • Diabetic kidney disease (reduction of proteinuria)
    • Chronic kidney disease progression

Key Features

  • Potent and selective ETA antagonist
  • Oral administration
  • Renal protective potential

Main Adverse Reactions

  • Peripheral edema
  • Fluid retention
  • Headache
  • Nasal congestion

Contraindications

  • Hypersensitivity to atrasentan hydrochloride
  • Severe fluid overload
  • Uncontrolled heart failure
  •  
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