Quick Details:Product Name:Oral Steroids Anti - Estrogen Arimidex
Formula: C17H19N5
Molecular Weight: 293.37
Package: 25kg/Drum
Storage: Cool and dry
Standard: Enterprise Standard
Markets: Global Additional
Packing: Foil Bag or tin
Policy: Re-Shipping PolicyExport
Appearance: White powder.
Quality standard: USP 35
Delivery: 5-7 Working Days 100%Safe&Timely
Category: Pharmaceutical raw materials and intermediates
Solubility: Freely soluble in methanol, acetone, ethanol and tetrahydrofuran. And very soluble in acetonitrile
The drug is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to gynecomastia and using moderate amounts of such steroids. Arimidex does not have the side effects of aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much moreso than Cytadren. It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests, or less preferably salivary tests, should be taken after the first week of use to determine if the dosing is correct.Three azole aromatase inhibitors are potent selective, it can inhibit the cytochrome P-450 dependent aromatase thereby blocking the biosynthesis of estrogen, but estrogen is the main factor that stimulates the growth of breast cancer cells.The treatment of breast cancer, especially for those with adjuvant hormone therapy after menopause after recurrence of women with advanced breast cancer. Specification:
Description |
White crystalline powder |
Complies |
Identification |
IRHPLCReactive |
Conform with standard IRConform with standard HPLCConform |
|
|
|
Total Impurity |
max.0.5% |
0.18% |
Total Unspecified Impurity |
max. 0.2% |
0.08% |
Individual unspecified impurlty |
max. 0.1% |
0.05% |
Related compound B |
max. 0.2% |
0.07% |
Related compound C |
max. 0.2% |
0.04% |
Related compound D |
max. 0.1% |
0.05% |
Related compound E |
max. 0.1% |
0.06% |
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|
|
Limit of ethylacetate |
max. 0.1% |
0.07% |
Melting point |
81.0~84.0ºC |
82.5~83.2ºC |
Water |
max. 0.3% |
0.21% |
Residue on ignition |
max. 0.1% |
0.07% |
Heavy Metals |
max.0.001% |
Complies |
Assay(HPLC) |
98.0%~102.0% |
99.8% |
Storage |
Cool and dry |