Limaprost cas 74397-12-9

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Home > Product > Limaprost cas 74397-12-9
Product
Limaprost cas 74397-12-9
Posting date : Jan 06, 2021
Membership
Free Member Scince Dec 09, 2019
FOB Price
1
Min. Order Quantity
1g
Supply Abillity
1kg/month
Port
shanghai
Payment Terms
L/C;D/A;D/P;T/T
Package
Packaging according to customer requirements
Keyword :
Category
Contact
Jin
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Product Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
Crene
Model Number
cas 74397-12-9
HS-CODE
-
Package & Delivery Lead Time
Package
Packaging according to customer requirements
Detailed Description

Limaprost(OP1206) is a PGE1 analog and potent platelet adhesion inhibitor. Target: Others Limaprost, an alprostadil (prostaglandin E1) analogue, is a vasodilator that increases blood flow and inhibits platelet aggregation. Limaprost is a n analog of PGE1 with structural modifications intended to give a prolonged half-life and greater potency. It is orally active in both guinea pigs and rats at doses of 100 mg/kg as an inhibitor of ADP and collagen induced platelet aggregation. It is 10-1,000 times more potent than PGE1 as a platelet adhesive inhibitor, measured in vitro. Intra-coronary injection (100 ng/kg) or intravenous injection (3 mg/kg) in anesthetized dogs causes vasodilation and increased coronary blood flow by 60-80%. Significant hypotensive effects were seen at 100 and 300 mg/kg orally in rats.

 

Related Prodcuts:  (+)-Cloprostenol;  Cloprostenol;  Misoprostol;  Carboprost;  Dinoprost Prostaglandin F2a


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