5630-53-5 Tibolone

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Product
5630-53-5 Tibolone
Posting date : Apr 25, 2017
Membership
Free Member Scince Apr 25, 2017
FOB Price
Negotiable
Min. Order Quantity
10g
Supply Abillity
1000Kg/Month
Port
Negotiable
Payment Terms
T/T, Western Union, MoneyGram,Bitcoin
Package
As you request
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Product Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
kafen
HS-CODE
-
Package & Delivery Lead Time
Package
As you request
Detailed Description
Anti Aging Estrogen Steroids CAS 5630-53-5 Tibolone Livial for Female Hormones Medicines
Basic Info.
Product name: TiboloneAlias: LIVIELLA; LIVIALCAS: 5630-53-5EINECS: 227-069-1Assay: 99% min.MF: C21H28O2MW: 312.45Appearance: White or off-white crystal powderGrade: Pharmaceutical GradeStorage: Shading, confined preservationUsage: It is a synthetic hormone-type drug which is used mainly for hormone replacement therapy in post-menopausal women.
Product Description: 
Tibolone (Livial/Liviella) is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. Tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for ER alpha. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile. It has also been investigated as a possible treatment for female sexual dysfunction.
Tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for ER alpha. It is used mainly for treatment of endometriosis,as well as hormone replacement therapy in post-menopausal women. Tibolone has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile.It has also been investigated as a possible treatment for female sexual dysfunction. 
Applications:
Tibolone is an estrogen-like compound used for the treatment of the symptoms associated with menopausal transition (i.e., climacteric symptoms) and also for the treatment of osteoporosis.Three major metabolites of tibolone are responsible for its tissue selective mechanism of action. Conversion into 3α- and 3β-hydroxy-tibolone results in estrogenic effects in brain, vagina, and bone. The  isomer has progestrogenic and androgenic effects and does not cause estrogenic stimulation in the endometrium.A two-year longitudinal study indicates that low doses (1.25-2.5 mg) of tibolone effectively relieve climacteric symptoms and prevent loss of bone mass in early postmenopausal women.

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