anbenitamab

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Selling leads
anbenitamab
Posting date : Mar 16, 2026
Membership
Free Member Scince Jul 07, 2025
FOB Price
$314.5
Min. Order Quantity
10g
Supply Abillity
Stock
Port
Ningbo
Payment Terms
T/T 100%
Package
1g,10g,20g,
Keyword :
chemical
Category
Contact
Lunar
Selling Leads Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
Jinlan
HS-CODE
-
Package & Delivery Lead Time
Package
1g,10g,20g,
Detailed Description
CAS No.：2367012-88-0
Drug Type：Recombinant humanized bispecific antibody (IgG1κ)
Code：KN026

Description

A HER2-targeted bispecific antibody developed by Alphamab Oncology.
Dual binding to HER2 extracellular domains II and IV (mimicking trastuzumab and pertuzumab).

Mechanism of Action

  • Dual epitope blockade of HER2 signaling
  • Inhibits ligand-independent dimerization and HER2-HER3 heterodimerization
  • Potent suppression of PI3K/AKT and MAPK pathways
  • Enhanced ADCC-mediated cytotoxicity

Indications (Clinical/Investigational)

  • Approved NDA status: HER2-positive locally advanced/recurrent/metastatic gastric/gastroesophageal junction cancer (post-trastuzumab failure, combined with chemotherapy)康宁杰瑞
  • Investigational: HER2-positive breast cancer and HER2-low solid tumors

Key Features

  • Superior target affinity and pathway inhibition vs. HER2 monotherapies
  • Activity in trastuzumab-resistant settings
  • Favorable safety profile (limited cardiac toxicity)
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