(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-nitrophenyl carbonate

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Selling leads
(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-nitrophenyl carbonate
Posting date : Apr 15, 2026
Membership
Free Member Scince Jul 07, 2025
FOB Price
$314.5
Min. Order Quantity
10g
Supply Abillity
Stock
Port
Ningbo
Payment Terms
T/T 100%
Package
1g,10g,20g,
Keyword :
Category
Contact
Lunar
Selling Leads Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
Jinlan
HS-CODE
-
Package & Delivery Lead Time
Package
1g,10g,20g,
Detailed Description

Product Description

This compound is a specialized ester prodrug intermediate widely used in pharmaceutical synthesis, particularly for constructing dioxolane ester prodrugs to improve oral bioavailability of acidic drugs such as β‑lactam antibiotics, NSAIDs, and other poorly absorbed active molecules.
It acts as a prodrug moiety donor, introducing the (5‑methyl‑2‑oxo‑1,3‑dioxol‑4‑yl)methyl group via carbonate linkage. After oral administration, the dioxolane ring is rapidly cleaved by esterases, releasing the parent active drug and improving solubility, permeability, and stability in the gastrointestinal tract.

Key Features

  • Efficient prodrug coupling reagent
  • Stable crystalline solid
  • High purity and low impurity profile
  • Optimized for API prodrug synthesis

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