(5-Methyl-[1,3,4]oxadiazol-2-yl)-acetic acid ethyl ester

China [CN]

Structural Characteristics: The molecule contains a [1,3,4] oxadiazole ring, which offers stability and conjugation. The presence of a methyl group at the 5-position increases steric hindrance and lipid solubility. The ethyl acetate group is linked to the oxadiazole ring via a carbon-carbon bond, giving the molecule both the characteristics of a heterocyclic compound and the properties of an ester.

Physical and Chemical Properties: It is typically a colorless to pale yellow liquid or solid, its physical state depending on its purity and temperature. Its boiling point, melting point, and other physical constants vary depending on the impurity content. It is soluble in common organic solvents such as ethanol, ether, and dichloromethane, but poorly soluble in water.

Chemical Properties: The ester group in the molecule exhibits typical properties of ester compounds, undergoing hydrolysis under acidic or alkaline conditions to produce the corresponding acid and alcohol. The methyl group on the oxadiazole ring can undergo substitution reactions under certain conditions.

Uses: It can be used as an organic synthesis intermediate for the preparation of a variety of compounds with biological activity or special functions. It has potential applications in medicinal chemistry, materials science, and other fields. For example, by modifying its structure and introducing other functional groups, drug molecules with pharmacological activities such as antibacterial and anti-inflammatory activities can be synthesized.