Acalabrutinib

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Selling leads
Acalabrutinib
Posting date : Jul 22, 2025
Membership
Free Member Scince Jun 27, 2025
FOB Price
detailed discussion
Min. Order Quantity
1
Supply Abillity
hundreds of kgs
Port
Shanghai Port
Payment Terms
detailed discussion
Package
Convenient package
Keyword :
Category
Contact
Lena
Selling Leads Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
Royal
Model Number
+86 15242851296
HS-CODE
-
Package & Delivery Lead Time
Package
Convenient package
Detailed Description

Acatinib and its metabolite ACP-5862 form covalent binding with the cysteine residue at position 481 of the active site of BTK, thereby inhibiting the activity of the BTK enzyme. And BTK serves as a signaling molecule for B-cell antigen receptors and cytokine receptor channels. In B cells, the activation of BTK signaling Chemicalbook is a necessary channel signal for promoting B cell proliferation, transport, chemotaxis and adhesion. Acatinib and its metabolites selectively block the BTK pathway without disrupting other molecular pathways that are important for platelets and immune function, thereby avoiding or reducing the occurrence of adverse reactions related to cancer therapy


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