CAS 566-48-3 Formestane

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CAS 566-48-3 Formestane
Posting date : Jan 31, 2018
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Product name: FormestaneAlias: LentaronCAS register number: 566-48-3Molecular formula: C19H26O3Molecular Weight:302.4126Melting point: 199-202°CAssay: 99%Appearance: white or light green crystalloidUsage: An antitumor drug. An aromatase inhibitor
Description:
Formestane (Lentaron) is a type I, steroidal aromatase inhibitor. It is used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. It is available as an intramuscular depot injection.
Formestane is often used to suppress estrogen production from anabolic steroids or prohormones. It also acts as a prohormone to 4-hydroxytestosterone, an active steroid which displays weak androgenic activity in addition to acting as a mild aromatase inhibitor.
Formestane has poor oral bioavailability and as such is no longer popular as many orally active aromatase inhibitors have been identified.

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