Avatoptinib's high selectivity for PDGFRA and KIT mutations makes it suitable for precise treatment of tumors with specific gene mutations. It has been proven effective in treating GIST patients with …
Calcipofen Acetate is the first antifungal drug among the acanthocyanins and has been approved for marketing by the U.S. Food and Drug Administration (FDA). It was launched in 2001 and has been approv…
ABT-199 plays a role in treating cancer by attacking an important protein called BCL-2. BCL-2 is one of the earliest discovered members of the BCL-2 protein family that regulates cell death. It is ass…
Midostaurin (MS) is an active derivative obtained through structural modification of an indolecarbazole alkaloid - staurosporine, which was isolated from Streptomyces Marine staurosporine culture medi…
Acatinib and its metabolite ACP-5862 form covalent binding with the cysteine residue at position 481 of the active site of BTK, thereby inhibiting the activity of the BTK enzyme. And BTK serves as a s…
Temozolomide is the first orally effective imidazotetrazine antitumor drug, belonging to the second-generation alkylating agents with anti-tumor activity. It does not require hepatic metabolic activat…
Verofenib is a small molecule BRAF kinase inhibitor that can selectively bind to the ATP-binding domain of mutant BRAF, thereby inhibiting the activation of this enzyme. The U.S. Food and Drug Adminis…
Pomalidomide, with the chemical name 4-amino-2 - (2, 6-dioxy-piperidin-3-yl) -isodihydroindole-1, 3-dione, is a thalidomide analogue and an immunomodulator with anti-tumor activity. In vitro cytologic…
2026 CHINA(GUANGZHOU) INT’L METAL & METALLURGY EXHIBITIONGoverned By: Ministry of Commerce of the People's Republic of China Department of Foreign Trad…
Bortezomib is the first proteasome inhibitor approved by the US FDA for multiple myeloma (a type of blood cancer). Reversible 26S proteasome inhibitor, a bar-shaped multi-protein granule, exists in th…
Ipilimumab is an anti-CTLA-4 antibody. CTLA-4 is expressed on the surface of T cells and is the first inhibitory receptor target used in clinical research. CTLA-4 exerts inhibitory functions during th…
Anastrozole is a potent and selective triazole aromatase inhibitor. It can inhibit the aromatase dependent on cytochrome P-450, thereby blocking the biosynthesis of estrogen, which is the main factor …
2026 China(Guangzhou)International Metal &Metallurgy ExhibitionTHE26th CHINA(GUANGZHOU)INT'STAINLESS STEEL INDUSTRY EXHIBITIONwww.stainlesssteelexpo.comGoverned By: Minist…
Paclitaxel is a monomer diterpene compound extracted from the bark of the natural plant Taxus chinensis. It is a complex secondary metabolite and currently the only known drug that can promote microtu…
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