Titanium is a lightweight metal known for its high strength, excellent corrosion resistance, and outstanding performance in both high and low temperatures. Titanium clad plates…
Nintedanib sulfonate is a small molecule inhibitor of multi-receptor tyrosine kinases and non-receptor tyrosine kinases. It was first approved by the US FDA in 2014 and was first developed and sold by…
Midotolin (MS) is an active derivative obtained through structural modification of staurosporine, an indolecarbazole alkaloid isolated from Marine Streptomycosis staurosporine culture medium in 1977. …
lapatinib, trade name Tykerb, is an oral reversible small molecule tyrosine kinase inhibitor targeting HER-1/HER-2. Lapatinib has a different mechanism of action from the humanized monoclonal antibody…
Vismodegib, trade name: Erivedge; It is one of the new anti-tumor drugs for the treatment of advanced cutaneous basal cell carcinoma (BCC), which was applied for and developed by Genentech Co., Ltd. a…
4-chloro-6, 7-bis (2-methoxyethoxy) quinazoline is a common organosynthetic molecule that can be used as a molecular backbone to participate in the modification of bioactive molecules and drug molecul…
Tukysa (Tucatinib)/Tucatinib (ONT-380) is an oral TKI(tyrosine kinase) inhibitor with high specificity for HER2. On April 17, 2020, the US FDA approved the combination of tucatinib with trastuzumab an…
(3S)-N-[5-[(2R)-2-(2, 5-difluorophenyl) -1-pyrrolidine] pyrazole [1, 5-a] pyrimidine-3-yl] -3-hydroxy-1-pyrrolidine formamide sulfate is an effective and selective oral ATP-competitive inhibitor of my…
Lopsitinib (TPX-0005) is a fourth-generation ALK inhibitor developed by TPTherapeutics, founded by Dr. Cui Jingrong. It is a broad-spectrum ALK, ROS1 and TRK inhibitor, mainly targeting multiple acqui…
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