Sofebuvir is a prodrug that can be metabolized into the active antiviral drug 2' -deoxy-2 '-α -fluorine -β -C-methyluridine 5' -monophosphate. Currently, it is in a Phase 3 clinical clinical trial for…
Elbaviragrelvir Tablets are a cutting-edge direct antiviral drug, suitable for the treatment of genotype 1 and genotype 4 hepatitis C. At present, there are approximately 10 million people infected wi…
Grazoprevir anhydrous (MK5172) is an inhibitor of Hepatitis C Virus NS3/4A Protease, and the IC50 values of HCV genotype 1a, 1B and 4 are 7pM, 4pM and 62pM, respectively.
Pibrentasvir (ABT-530) is a novel pan-genotype hepatitis C virus (HCV) NS5A inhibitor, and its EC50 value for HCV replicators containing NS5A genotypes 1 to 6 ranges from 1.4 pM to 5.0 pM.
Gleepvir is an oral RNA polymerase inhibitor that directly acts on the RNA polymerase of the virus, thereby inhibiting the growth and replication of the virus. It is mainly used in the treatment of he…
Entecavir monohydrate is a new type of cyclovaleryl guanosine anti-hepatitis B virus drug. Its pharmacological effect is similar to that of entecavir. Clinically, it is indicated for the treatment of …
Tenofovir alafolamine is a novel nucleotide-type reverse transcriptase inhibitor. After entering liver cells, the drug can be hydrolyzed into tenofovir. Tenofovir is subsequently phosphorylated by int…
Vemlidy (Tenofovir alafolamine fumarate, 25mg, once daily) has been approved by the US FDA for the treatment of chronic hepatitis B virus infection in compensatory liver disease. Vemlidy is an innovat…
Fumaric acid tenofovir is the Gilead listed companies to develop a kind of nucleotide antiviral drugs, in 2001, approved by the FDA for the treatment of human immunodeficiency virus (humanimmunodefici…
vildagliptin is another orally administered dipeptidyl peptidase-IV (DPP-IV) inhibitor following sitagliptin. It was approved for marketing in the European Union in 2008 by Novartis Pharmaceuticals GM…
Glimepirea is a long-acting antidiabetic drug of the third-generation sulfonylurea class. The main mechanism of its hypoglycemic effect is to stimulate pancreatic β cells to secrete insulin and partia…
Besagliflozin is an SGLT2 inhibitor. As a new type of hypoglycemic drug, SGLT2 inhibitors can increase the body's heat consumption, reduce fluid retention and increase the excretion of urine sugar by …
Canagliflozin is an SGLT2 inhibitor drug that can reduce blood sugar by breaking down glucose and excreting it through the kidneys. Besides good blood sugar control, The most remarkable feature of Can…
Miglitol, trade name Otiapin, is an α -glucosidase inhibitor with a pseudo-monosaccharide chemical structure. It inhibits more types of α -glucosidases than acarbose and voglitagbose. It does not caus…
dapagliflozin (ForxigaTM), a novel anti-diabetic drug jointly developed by Bristol-Myers Squibb and Astrazeneca, was approved for marketing by the European Medicines Agency (EMA) on November 12, 2012.…
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