CAS No. 75330-75-5 (Lovastatin )

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CAS No. 75330-75-5 (Lovastatin )
Posting date : Feb 19, 2014
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Identification of 75330-75-5 Name: Lovastatin (Related Reference) Molecular Formula: C24H36O5 CAS Registry Number: 75330-75-5 Molecular Structure: Lovastatin C24H36O5 (cas 75330-75-5) Molecular Structure This structure is also available as a 2d Mol file Chemical Properties Appearance: White solid Molecular Weight: 404.54 Density: 1.12 g/cm3 Boiling Point: 559.2 oC at 760 mmHg Melting Point: 175℃ Flash Point: 185.3 oC Storage Temperature: 2-8°C Refractive index: 320 ° (C=0.5, CH3CN) Solubility: 0.0004 mg/mL at 25 oC Biological Activity: Potent, competitive inhibitor of HMG-CoA reductase (K i = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo . Decreases CDK2, 4, 6 and cyclin E levels and induces G1 arrest and apoptosis in tumor cell lines in vitro . Stability: No data. Usage: An antihypercholesterolemic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase We invite you to visit our website http://www.guidechem.com/reference/dic-27208.html

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