Lenacapavir intermediate LPE-1

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Product
Lenacapavir intermediate LPE-1
Posting date : Apr 28, 2026
Membership
Free Member Scince Dec 22, 2025
FOB Price
1
Min. Order Quantity
1kg
Supply Abillity
50000kg
Port
Beijing
Payment Terms
100% TT in Advance
Package
25kg/bags;10kg/bgs;1kg/bags
Keyword :
Category
Contact
Winnie Wang
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Product Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
JINLAN Brand
Model Number
2375020-20-3
HS-CODE
-
Package & Delivery Lead Time
Package
25kg/bags;10kg/bgs;1kg/bags
Delivery Lead Time
7-14 workdays
Detailed Description
Product Name: N-((S)-1-(3-(3-amino-4-chloro-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide
Synonyms: Lenacapavir Impurity 38
CAS No.: 2375020-20-3
Molecular Formula: C₃₈H₃₀ClF₁₀N₇O₃S
Molecular Weight: 890.19 g/mol
Key Specifications:
  • Predicted Boiling Point: 902.7 ± 65.0 °C (at 760 Torr)
  • Predicted Density: 1.606 ± 0.14 g/cm³ (at 25 °C)
  • Predicted pKa: 12.52 ± 0.46
  • Appearance: Solid (typical)
  • Purity: ≥98% (determined by HPLC; full batch-specific COA provided)
  • Storage: Recommended to store at -20°C, protected from light and moisture
Product Overview:
This is a late-stage intermediate/key impurity in the manufacturing process of Lenacapavir (GS-6207), the novel HIV-1 capsid inhibitor. It contains the full API core structure and stereochemistry, making it critical for process validation, impurity profiling, and quality control in anti-HIV drug development.
Applications:
  • Reference standard/impurity standard for Lenacapavir drug development
  • Used in pharmaceutical R&D, process optimization, and forced degradation studies
  • Applied in regulatory submissions (IND/ANDA/DMF) for anti-HIV drugs
Additional Information:
  • Full analytical documentation (¹H NMR, LC-MS, chiral HPLC, elemental analysis) available upon request
  • Custom synthesis and bulk production quantities are available
  • For research and laboratory use only; not intended for direct human administration.

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