Lenacapavir intermediate LPE-3

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Product
Lenacapavir intermediate LPE-3
Posting date : Apr 28, 2026
Membership
Free Member Scince Dec 22, 2025
FOB Price
1
Min. Order Quantity
1kg
Supply Abillity
50000kg
Port
Beijing
Payment Terms
100% TT in Advance
Package
25kg/bags;10kg/bgs;1kg/bags
Keyword :
Category
Contact
Winnie Wang
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Product Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
JINLAN Brand
Model Number
2375019-85-3
HS-CODE
-
Package & Delivery Lead Time
Package
25kg/bags;10kg/bgs;1kg/bags
Delivery Lead Time
7-14 workdays
Detailed Description
Product Name: (S)-1-(3-Bromo-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethan-1-amine
Synonyms: Lenacapavir Impurity 2
CAS No.: 2375019-85-3
Molecular Formula: C₁₉H₁₉BrF₂N₂O₂S
Molecular Weight: 457.33 g/mol
Key Specifications:
  • Predicted Boiling Point: 549.3 ± 50.0 °C
  • Predicted Density: 1.51 ± 0.1 g/cm³
  • Predicted pKa: 7.60 ± 0.50
  • Appearance: Solid (typical)
  • Purity: ≥98% (determined by HPLC; full batch-specific COA provided)
  • Storage: Recommended to store at -20°C, protected from light and moisture
Product Overview:
This is a key advanced chiral intermediate in the multi-step synthesis of Lenacapavir (GS-6207), the novel HIV-1 capsid inhibitor. It features a chiral amine, bromopyridine, and butynyl-sulfonyl side chain, representing a critical coupling step in the API manufacturing route.
Applications:
  • Advanced intermediate for Lenacapavir (anti-HIV drug) manufacturing and process development
  • Used in synthetic route optimization, pilot scale-up, and manufacturing process validation
  • Applied in chiral synthesis and coupling reaction development
Additional Information:
  • Full analytical documentation (¹H NMR, LC-MS, chiral HPLC, elemental analysis) available upon request
  • Custom synthesis and bulk production quantities are available
  • For research and laboratory use only; not intended for direct human administration.
 

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