Lenacapavir intermediate LPA

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Product
Lenacapavir intermediate LPA
Posting date : Apr 28, 2026
Membership
Free Member Scince Dec 22, 2025
FOB Price
1
Min. Order Quantity
1kg
Supply Abillity
50000kg
Port
Beijing
Payment Terms
100% TT in Advance
Package
25kg/bags;10kg/bgs;1kg/bags
Keyword :
Category
Contact
Winnie Wang
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Product Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
JINLAN Brand
Model Number
1620056-83-8
HS-CODE
-
Package & Delivery Lead Time
Package
25kg/bags;10kg/bgs;1kg/bags
Delivery Lead Time
7-14 workdays
Detailed Description
Product Name: 2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetic acid
Synonyms: Lenacapavir Intermediate; Apremilast Impurity 123
CAS No.: 1620056-83-8
Molecular Formula: C₁₀H₇F₅N₂O₂
Molecular Weight: 282.17 g/mol
Key Specifications:
  • Appearance: White to off-white solid
  • Predicted Boiling Point: 325.8 ± 42.0 °C
  • Predicted Density: 1.96 ± 0.1 g/cm³
  • Predicted pKa: 3.49 ± 0.10
  • Storage: Room temperature (general recommendation; for long-term storage, keep at -20°C)
  • Purity: ≥98% (determined by HPLC; full batch-specific COA provided)
Product Overview:
This is a key early-stage chiral intermediate in the synthesis of Lenacapavir (GS-6207), the novel HIV-1 capsid inhibitor. It features the core cyclopropa-fused pyrazole structure with high stereochemical purity, serving as a foundational building block for the multi-step synthetic route of the API.
Applications:
  • Early-stage chiral intermediate for Lenacapavir (anti-HIV drug) manufacturing and process development
  • Used in synthetic route optimization, pilot scale-up, and chiral resolution studies
  • Applied in coupling reaction development for the construction of complex drug structures
Additional Information:
  • Full analytical documentation (¹H NMR, LC-MS, chiral HPLC, elemental analysis) available upon request
  • Custom synthesis and bulk production quantities are available
  • For research and laboratory use only; not intended for direct human administration.

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