Orforglipron Intermediate M-2

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Product
Orforglipron Intermediate M-2
Posting date : Apr 27, 2026
Membership
Free Member Scince Apr 24, 2026
FOB Price
1
Min. Order Quantity
1kg
Supply Abillity
50000kg
Port
Beijing
Payment Terms
100% TT in Advance
Package
25kg/bags;10kg/bgs;1kg/bags
Keyword :
Category
Contact
Winnie Wang
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Product Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
JINLAN Brand
Model Number
2212021-82-2
HS-CODE
-
Package & Delivery Lead Time
Package
25kg/bags;10kg/bgs;1kg/bags
Delivery Lead Time
7-14 workdays
Detailed Description
Product Name:
1H-Indole-2-carboxamide, 1-[(1S,2S)-1-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)-2-methylcyclopropyl]-N-methyl-N-phenyl-5-[(4S)-tetrahydro-2,2-dimethyl-2H-pyran-4-yl]-
Synonyms:
Orforglipron Intermediate, Olagliflon Intermediate Impurity 97, Olagliflon Intermediate-6
CAS No.: 2212021-82-2
Molecular Formula: C₂₉H₃₂N₄O₄
Molecular Weight: 500.59 g/mol

Key Specifications & Properties:
  • Appearance: White to off-white solid (standard for high-purity pharmaceutical intermediates)
  • Predicted Density: 1.34 ± 0.1 g/cm³
  • Predicted pKa: 7.30 ± 0.20
  • Stereochemistry: Multi-chiral center (1S,2S,4S) configuration, ≥98% enantiomeric purity
  • Purity: ≥98% (determined by HPLC; full batch-specific COA provided)
  • Storage: Store at -20°C under inert atmosphere; protect from light and moisture

Application & Use Case:
This compound is a critical synthetic intermediate and impurity reference standard for Orforglipron (Olagliflon), an oral GLP-1 receptor agonist under clinical development. It is widely used in:
  • Pharmaceutical process development and scale-up
  • Analytical method validation (HPLC, LC-MS, chiral chromatography)
  • Stability testing and forced degradation studies
  • Regulatory submissions (IND/ANDA/DMF) requiring impurity characterization

Additional Information:
  • Full analytical documentation available: HPLC, ¹H NMR, ¹³C NMR, LC-MS, elemental analysis, and COA
  • Custom synthesis and bulk production quantities available upon request
  • For research and laboratory use only; not intended for human or veterinary therapeutic administration.

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