2-(p-Tolyl)thiazole-4-carboxylic acid

Basic information:

Molecular formula: C₁₁H₉NO₂S

Molecular weight: 219.26

Physical and chemical properties: Usually solid, the appearance may be white to light yellow powder or crystal. Because the molecule contains polar carboxyl and non-polar p-toluene and thiazole rings, it is speculated that it is insoluble in water and soluble in some organic solvents, such as dichloromethane, N,N-dimethylformamide, etc.

Uses: As an important organic synthesis intermediate, it can be used to prepare a variety of biologically active compounds. Its thiazole ring and carboxyl group have high reactivity, and can construct new chemical bonds through esterification, amidation and other reactions, and then be used to synthesize drugs, pesticides, etc. For example, it can participate in the construction of drug molecular structures with pharmacological activities such as antibacterial and anti-inflammatory