1. Basic information
Chinese name: (2R)-2-bromopropionic acid methyl ester
English name: (R)-Methyl 2-bromopropanoate (or (R)-2-Bromopropionic acid methyl ester)
CAS number: 54452-41-4
Molecular formula: C₄H₇BrO₂
Molecular weight: 167.00 g/mol
Stereochemistry: The molecule contains a chiral carbon atom (carbon 2), the configuration is R type, and it is optically active.
2. Physical and chemical properties
Appearance and properties: It is a colorless and transparent liquid at room temperature, and may have a slight pungent odor.
Melting point: There is no clear public data (it is speculated to be a low melting point liquid).
Boiling point: about 145-150℃ (normal pressure), or 60-62℃ (15 mmHg, reduced pressure distillation temperature).
Density: 1.45-1.48 g/cm³ (25℃), which is more dense than water.
Optical rotation: [α]ₙ²⁰ (solvents such as ethanol) about + 10° to + 15° (specific values vary depending on purity and measurement conditions).
Solubility: Soluble in organic solvents such as methanol, ethanol, ether, and dichloromethane, and difficult to dissolve in water.
Stability: Stable at room temperature, but prone to hydrolysis in strong alkali, and may be debrominated in reducing agents. Avoid contact with strong alkaline substances and metal reducing agents.