methyl (2S)-2-methyl-3-oxobutanoate

Basic information

Molecular formula: C₇H₁₂O₃

Molecular weight: 144.17

CAS number: 17094-21-2

English alias: Methyl 2-methylacetoacetate, Methyl 2-methyl-3-oxobutyrate, etc.

Physical and chemical properties

Appearance: colorless and transparent liquid.

Density: 1.019g/mL at 25℃.

Boiling point: 187℃.

Flash point: 63℃ (closed cup).

Solubility: insoluble in water, soluble in common organic solvents.

Uses

Mainly used as pharmaceutical and pesticide intermediates, can be used to prepare a variety of biologically active compounds. It can also be used in the Japp-Klingemann reaction to prepare hydrazones from β-keto acids and aromatic diazonium salts.

Storage conditions

It should be stored in a cool, ventilated warehouse, away from fire and heat sources, avoid contact with incompatible substances such as strong oxidants and strong alkalis, and be stored and transported in accordance with the requirements for flammable liquids.

Safety information

Inhalation, skin contact and accidental swallowing may be harmful, and it is irritating to the eyes, respiratory tract and skin. Pay attention to protection when using it and wear appropriate protective equipment.