basic principle of freeze drying

The basic principle of freeze drying is based on the three-state change of water. Water has solid, liquid and gaseous states, and the three states can be converted and coexist. At the same time, water, ice, and water vapor can coexist and balance each other. Under the high vacuum state, the sublimation principle is used to make the moisture in the pre-frozen material not be melted by the ice, and is directly removed into the water vapor by the ice state, thereby achieving the purpose of freeze-drying.

    The lyophilized product has a sponge shape, no shrinkage, excellent rehydration, and very little water content. After storage, it can be stored and transported at room temperature for a long time. Since vacuum freeze-drying has unparalleled advantages in other drying methods, it has become more and more popular since its inception, and has become increasingly popular in medicine, biological products and food. Biological products such as serum, strains, Chinese and Western medicine are mostly biologically active substances, and vacuum freeze-drying technology also provides a good solution for preserving biological activity.

    The drying box is a vacuum sealed low-pressure container. The materials are all made of stainless steel. They can withstand positive and negative pressures. They meet the requirements of steam sterilization. The seals are made of high temperature resistant and low temperature resistant silicone rubber. The insulation layer is made of closed foam elastic insulation material. The rectangular box with high rate has a drain port at the bottom and an observation window on the side. The box is also equipped with a pressure gauge, a temperature measuring resistor, a venting valve, an infiltration valve, a safety valve and a spray inlet joint.

    The energy required for the cooling and opening of the food is transmitted to the shelf through the heat exchange medium and then to the food. The shelf is made of special hollow splint, which has high strength and good sealing. The shelf assembly is installed in the freeze-drying box through the bracket, and a plate layer is set as the heat radiation compensation plate on the uppermost layer to ensure that the space of the food in the box is in the same temperature environment, and the sides and the back of the shelf are both Set the rails to prevent the food tray or food from coming off the shelf.

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