Human Growth Hormone Active Pharmaceutical Ingredient Gonadorelin Acetate 71447-49-9

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Product
Human Growth Hormone Active Pharmaceutical Ingredient Gonadorelin Acet...
Posting date : Mar 25, 2017
Membership
Free Member Scince Mar 24, 2017
FOB Price
$1
Min. Order Quantity
2mg
Supply Abillity
2000kg/week
Port
Guangzhou
Payment Terms
T/T, Bank Transfer, Western Union, Paypal
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According to your requirements
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Product Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
Kafen
Model Number
33515-09-2
HS-CODE
-
Package & Delivery Lead Time
Package
According to your requirements
Delivery Lead Time
Within 12 hours after receiving your payment
Detailed Description
Human Growth Hormone Active Pharmaceutical Ingredient Gonadorelin Acetate 71447-49-9
Basic Info.
Name:GonadorelinOther Name: LH-RH, human, GonadorelineCAS:33515-09-2Purity (HPLC): 98.0%min.Appearance: White powderMolecular Formula: C59H83N17O17Molecular Weight: 1302.39Single Impurity (HPLC): 0.5%maxAmino Acid Composition: ±10% of theoreticalPeptide Content (N%): ≥80.0% Water Content(Karl Fischer): ≤8.0%Acetate Content(HPIC): ≤10.0%Specific Rotation (20/D): -55.0~-65.0°(c=1 1%HAc)MS (ESI): ConsistentMass Balance: 95.0~105.0%
Description: Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary.
GnRH is available as gonadorelin hydrochloride(Factrel®)and gonadorelin diacetate tetrahydrate(Cystorelin®)for injectable use. Studies have described it being used via an infusion pump system to induce ovulation in patients with hypothalamic hypogonadism. It is also used in veterinary medicine as a treatment for cattle with cystic ovarian disease.
 Application: Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use.

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