Calcitriol CAS No32222-06-3

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Product
Calcitriol CAS No32222-06-3
Posting date : Nov 04, 2016
Membership
Free Member Scince Nov 04, 2016
FOB Price
95USD/MG
Min. Order Quantity
100mg
Supply Abillity
500kgs per month
Port
SHENZHEN
Payment Terms
TT or L/C
Package
1MG/bottle
Keyword :
Category
Contact
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Product Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
Dieckmann
HS-CODE
2804-10
Package & Delivery Lead Time
Package
1MG/bottle
Delivery Lead Time
within 5 days after payment confirmed in our bank
Detailed Description
Calcitriol CAS No32222-06-3
 
Detailed Information:
Name
1α,25-Dihydroxyvitamin D3
CAS No
32222-06-3
Synonym
Calcitriol
1,25-Dihydroxycholecalciferol
Molecular Weight
416.64
M.F:
C27H44O3
Purity
99%min
Mp
119℃
MDL Number
MFCD00867079
EINECS No
250-963-8
Appearance
White powder
Medicine Grade
USP
Grade Standard
Medical stand
Model Number
API
Model Number
API
Documents available
COA,MSDS,NMR,HPLC
Certificate
SGS
Usage
Pharmaceuticals
Molecular Weight
416.64
Packing
100mg,1g,5g,25g,100g/bottle
Place of origin
China
Safety Description
S36/37/39/S45
storage
Store at -20° C,in N2, Keep from light.
 
Description:
 
Calcitriol  is a metabolite of the secosteroid vitamin D3. This hormone stimulates intestinal calcium transport at a much higher rate than vitamin D3 and hydroxy D3, and is considered to represent the biologically active form of vitamin D3. In addition to regulating the movement of calcium in the blood and bone, 1α,25-Dihydroxyvitamin D3 participates in developmental regulation and signaling. It stimulates an increase in protein kinase C levels with an effect on the regulation of c-myc transcription and activation of Raf kinase. 1α,25-Dihydroxyvitamin D3 is shown to increase the synthesis of prostacyclin with a correlated increase in cyclooxygenase activity, indicating a further role in vascular regulation. 1α,25-Dihydroxyvitamin D3 (Calcitriol) is an activator of PKC and VDR.
Appearance
White or almost white crystals
Conform
Solubility
Practically insoluble in water, freely soluble in alcohol, soluble in fatty oils
Conform
Identification
Infrared spectrum corresponds to that of the standard preparation
Conform
The retention time of the major peak in the chromatogram corresponds to that in the chromatogram of standard preparation
Conform
Related Compounds
Trazoline adduct of pre-calcitriol:NMT 0.5%
ND
Trans-calcitriol: NMT 0.5%
0.17%
1β-Calcitriol: NMT 0.5%
ND
Any other individual impurity: NMT 0.1%
Conform
Total impurities: NMT 0.1%
0.28%
Purity
NLT 99.0%
99.72%
Loss on Drying
NMT 0.5%
<0.05%
Heavy Metals
NMT 20ppm
Conform
Residue on Ignition
NMT 0.1%
<0.05%
Assay
97.0~103.0%
99.5%
 
Application:
1. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover.
2. Calcitriol (1,25-Dihydroxyvitamin D3; Rocaltrol )exhibits antitumor activity
3. Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells
 
Features :
1.Any inquiries will be replied within 12 hours.2. Dedication to quality, supply & service.3. Strictly on selecting raw materials.4. OEM/ODM Available.5. Reasonable & competitive price, fast lead time.6. Sample is available for your evaluation & Formulation development.7. Faster delivery:Sample order in stock and 3-7 days for bulk production.8. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.9. After-Sale Service:  International Authorized Third-Party Test For The Products You Demand.
 
 
Contact :
If you have any further questions or need a sample,Please do not hesitate to contact us.
ShenZhen Dieckmann Technology Development Co., LTDShenZhen Address:2floor,3 building, Maluan Make Place,2-10south of Jinlong Road, Pingshan New district,ShenzhenZip code: 518172Tel: 86-755-89213952Fax: 86-755-84813563Email: sale@dkmchem.com
 

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