Velpatasvir is a pangenotypic, oral, hepatitis C virus (HCV) NS5A inhibitor used in combination with sofosbuvir for the treatment of all major HCV genotypes.
Sofosbuvir is an oral, direct-acting antiviral (DAA) prodrug and a nucleotide analog inhibitor of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, used across all HCV genotypes.
Elbasvir is a pangenotypic, oral, hepatitis C virus (HCV) NS5A inhibitor used in combination with grazoprevir for the treatment of chronic HCV genotype 1 or 4 infection.
Grazoprevir is a macrocyclic, pangenotypic, second-generation hepatitis C virus (HCV) NS3/4A protease inhibitor used in combination with elbasvir for the treatment of chronic HCV genotype 1 or 4 infec…
Glecaprevir is a pangenotypic, oral, hepatitis C virus (HCV) NS3/4A protease inhibitor used in combination with pibrentasvir for the treatment of chronic HCV infection.
Tenofovir alafenamide is a next-generation oral prodrug of tenofovir, a nucleotide reverse transcriptase inhibitor (NtRTI) with enhanced lymphoid cell delivery and improved renal and bone safety profi…
Tenofovir alafenamide hemifumarate is the hemifumarate salt of the prodrug tenofovir alafenamide (TAF), a next-generation nucleotide reverse transcriptase inhibitor (NtRTI) with improved safety and ta…
Tenofovir disoproxil fumarate is the fumarate salt of the prodrug tenofovir disoproxil, a nucleotide reverse transcriptase inhibitor (NtRTI) used to treat HIV-1 infection and chronic hepatitis B.
Vemurafenib is an oral, small-molecule, selective inhibitor of BRAF kinase used to treat certain BRAF V600 mutation-positive cancers, notably metastatic melanoma.
Vutrisiran is a subcutaneously administered, small interfering RNA (siRNA) therapeutic that targets and degrades transthyretin (TTR) mRNA to treat transthyretin-mediated amyloidosis.
Grapiprant is an oral, selective antagonist of the prostaglandin E2 (PGE2) EP4 receptor, originally developed for the treatment of pain and inflammation associated with osteoarthritis in dogs.
Tazobactam Sodium is the sodium salt of tazobactam, a β-lactamase inhibitor used in combination with β-lactam antibiotics to extend their antimicrobial spectrum.
Icotrokinra (JNJ2113) is an oral, first-in-class, anti-inflammatory biologic drug candidate and an interleukin-23 (IL-23) receptor antagonist peptide developed for the treatment of immune-mediated dis…
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