Larotrectinib sulfate is the sulfate salt of larotrectinib, a first-in-class, highly selective, and potent oral inhibitor of the tropomyosin receptor kinase (TRK) family, used to treat solid tumors ha…
Repotrectinib is an oral, next-generation, macrocyclic tyrosine kinase inhibitor designed to potently inhibit ROS1 and TRK kinases, particularly effective against solvent-front mutations that cause re…
Ensartinib is an oral, potent, and highly selective second-generation inhibitor of anaplastic lymphoma kinase (ALK), developed to overcome resistance and improve efficacy against central nervous syste…
Cabozantinib S-malate is the S-malate salt of the oral, multi-targeted tyrosine kinase inhibitor cabozantinib, primarily used in the treatment of advanced renal cell carcinoma, hepatocellular carcinom…
Crizotinib is an oral, first-in-class, small-molecule inhibitor of anaplastic lymphoma kinase (ALK), ROS1, and MET tyrosine kinases, primarily used to treat ALK-positive or ROS1-positive non-small cel…
Capmatinib is an oral, selective, and potent small-molecule inhibitor of the mesenchymal-epithelial transition (MET) tyrosine kinase, used in the treatment of metastatic non-small cell lung cancer har…
Niraparib tosylate is the tosylate salt form of the poly (ADP-ribose) polymerase (PARP) inhibitor niraparib, used in the maintenance treatment of certain platinum-sensitive, recurrent cancers.
Sorafenib is an oral, small-molecule, multi-targeted tyrosine kinase inhibitor (TKI) and the first systemic agent shown to improve survival in advanced hepatocellular carcinoma (HCC).
Lenalidomide is an oral immunomodulatory drug (IMiD) derived from thalidomide, used in the treatment of multiple myeloma, myelodysplastic syndromes, and certain lymphomas.
Olaparib is an oral, first-in-class poly (ADP-ribose) polymerase (PARP) inhibitor used in the treatment of cancers with deficiencies in homologous recombination repair (HRR), particularly those harbor…
Abiraterone acetate is an oral prodrug of abiraterone, a selective and irreversible inhibitor of cytochrome P450 17A1 (CYP17A1), used in the treatment of metastatic castration-resistant prostate cance…
Axitinib is an oral, potent, and selective second-generation inhibitor of vascular endothelial growth factor receptors (VEGFRs), used in the treatment of advanced renal cell carcinoma (RCC).
Pazopanib is an oral, small-molecule, multi-targeted tyrosine kinase inhibitor (TKI) used in the treatment of advanced renal cell carcinoma and soft tissue sarcomas.
Elvitegravir is a once-daily, HIV-1 integrase strand transfer inhibitor (INSTI) that requires pharmacokinetic boosting (e.g., with cobicistat) and is used in combination antiretroviral therapy.
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