Vildagliptin is an oral antihyperglycemic agent belonging to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors, a first-line therapeutic option for the management of type 2 diabetes mellitus (T2D…
Midostaurin is an oral, first-generation, multi-targeted kinase inhibitor that potently inhibits FLT3, KIT, and other kinases, used in combination with chemotherapy for the treatment of newly diagnose…
Erlotinib hydrochloride is the hydrochloride salt of erlotinib, an oral, first-generation, reversible tyrosine kinase inhibitor that selectively targets the epidermal growth factor receptor (EGFR), us…
Larotrectinib sulfate is the sulfate salt of larotrectinib, a first-in-class, highly selective, and potent oral inhibitor of the tropomyosin receptor kinase (TRK) family, used to treat solid tumors ha…
Capmatinib is an oral, selective, and potent small-molecule inhibitor of the mesenchymal-epithelial transition (MET) tyrosine kinase, used in the treatment of metastatic non-small cell lung cancer har…
Pazopanib is an oral, small-molecule, multi-targeted tyrosine kinase inhibitor (TKI) used in the treatment of advanced renal cell carcinoma and soft tissue sarcomas.
Etravirine is a second-generation, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination regimens for the treatment of multidrug-resistant HIV-1 infection.
Elbasvir is a pangenotypic, oral, hepatitis C virus (HCV) NS5A inhibitor used in combination with grazoprevir for the treatment of chronic HCV genotype 1 or 4 infection.
Vemurafenib is an oral, small-molecule, selective inhibitor of BRAF kinase used to treat certain BRAF V600 mutation-positive cancers, notably metastatic melanoma.
Vutrisiran is a subcutaneously administered, small interfering RNA (siRNA) therapeutic that targets and degrades transthyretin (TTR) mRNA to treat transthyretin-mediated amyloidosis.
Grapiprant is an oral, selective antagonist of the prostaglandin E2 (PGE2) EP4 receptor, originally developed for the treatment of pain and inflammation associated with osteoarthritis in dogs.
Tazobactam Sodium is the sodium salt of tazobactam, a β-lactamase inhibitor used in combination with β-lactam antibiotics to extend their antimicrobial spectrum.
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