Vildagliptin is an oral antihyperglycemic agent belonging to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors, a first-line therapeutic option for the management of type 2 diabetes mellitus (T2D…
Midostaurin is an oral, first-generation, multi-targeted kinase inhibitor that potently inhibits FLT3, KIT, and other kinases, used in combination with chemotherapy for the treatment of newly diagnose…
Erlotinib hydrochloride is the hydrochloride salt of erlotinib, an oral, first-generation, reversible tyrosine kinase inhibitor that selectively targets the epidermal growth factor receptor (EGFR), us…
Selitrectinib is an investigational, oral, next-generation, highly selective TRK kinase inhibitor, specifically designed to overcome acquired resistance to prior TRK inhibitor therapy, particularly th…
Larotrectinib sulfate is the sulfate salt of larotrectinib, a first-in-class, highly selective, and potent oral inhibitor of the tropomyosin receptor kinase (TRK) family, used to treat solid tumors ha…
Repotrectinib is an oral, next-generation, macrocyclic tyrosine kinase inhibitor designed to potently inhibit ROS1 and TRK kinases, particularly effective against solvent-front mutations that cause re…
Ensartinib is an oral, potent, and highly selective second-generation inhibitor of anaplastic lymphoma kinase (ALK), developed to overcome resistance and improve efficacy against central nervous syste…
Crizotinib is an oral, first-in-class, small-molecule inhibitor of anaplastic lymphoma kinase (ALK), ROS1, and MET tyrosine kinases, primarily used to treat ALK-positive or ROS1-positive non-small cel…
Capmatinib is an oral, selective, and potent small-molecule inhibitor of the mesenchymal-epithelial transition (MET) tyrosine kinase, used in the treatment of metastatic non-small cell lung cancer har…
Pazopanib is an oral, small-molecule, multi-targeted tyrosine kinase inhibitor (TKI) used in the treatment of advanced renal cell carcinoma and soft tissue sarcomas.
Etravirine is a second-generation, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination regimens for the treatment of multidrug-resistant HIV-1 infection.
Elbasvir is a pangenotypic, oral, hepatitis C virus (HCV) NS5A inhibitor used in combination with grazoprevir for the treatment of chronic HCV genotype 1 or 4 infection.
Vemurafenib is an oral, small-molecule, selective inhibitor of BRAF kinase used to treat certain BRAF V600 mutation-positive cancers, notably metastatic melanoma.
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