Emtricitabine

China [CN]

Emtricitabine Basic Information

Chemical Name: 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one

CAS Number: 143491-57-0

Molecular Formula: C₈H₁₀FN₃O₃S

Molecular Weight: 247.24 g/mol

Common Synonyms: Emtricitabine, FTC, (-)-FTC, Emtriva® (trade name)

Core Uses

Anti-HIV-1 nucleoside reverse transcriptase inhibitor (NRTI)

Used in combination antiretroviral therapy for HIV-1 infection

Also used for pre-exposure prophylaxis (PrEP) against HIV

Key Physicochemical Properties

Appearance: White to off-white crystalline powder

Solubility: Easily soluble in water, methanol, ethanol

Melting Point: Approximately 153–155°C

Chirality: (2R,5S) configuration, single isomer

Common Information for International Trade/Supply Chain

Product Type: Active Pharmaceutical Ingredient (API) / Intermediate

Main Applications: Anti-HIV drug formulations, combination formulations (e.g., in combination with tenofovir)

Quality Standards: USP, EP, in-house standards

Packaging: 25kg/drum or as per customer requirements