di-tert-butyl2,2'-(((((2R,5R)-1-(3,5-difluoro-4-(4-(4-fluorophenyl)piperidin-1-yl)phenyl)pyrrolidine-2,5-diyl)bis(5-fluoro-2-nitro-4,1-phenylene))bis(azanediyl))bis(carbonyl))(2S,2'S)-bis(pyrrolidine-1-carboxylate)

China [CN]

1. Appearance: Pale yellow to off-white crystalline powder (contains nitroaromatic ring; the higher the purity, the lighter the color; the nitro group is prone to slight discoloration); 2. Solubility: Slightly soluble in water, readily soluble in dichloromethane, tetrahydrofuran, and N,N-dimethylformamide (DMF), soluble in ethyl acetate, sparingly soluble in methanol/petroleum ether (due to multiple fluorine substitutions + nitro group + Boc group, it exhibits significant lipophilicity); 3. Stability: Stable under sealed vacuum storage at room temperature in the dark (recommended ≤20℃), avoid strong acids (Boc deprotection), strong reducing agents (nitro group reduction), high temperatures (≥80℃ easily leads to Boc deprotection/nitro group decomposition), and strong light (nitroaromatic ring is prone to photolysis); 4. Melting point: Expected 180~200℃ (multiple chiral centers + multiple heterocycles + nitro group, resulting in a high melting point).