(S)-3-Aminobutanenitrile hydrochloride

China [CN]

CAS No. 103039-78-1 (Unique identifier, core basis for customer inquiries/customs clearance/supplier communication)

Molecular Formula: C₄H₉ClN₂

Molecular Weight: 120.58 (Used for molar concentration calculation and product quantification; molecular weight of the hydrochloride form includes the Cl atom)

Appearance: White to off-white crystalline powder (common form for industrial grade, lighter color indicates higher purity)

Core Uses: 1. Chiral drug intermediate: Used in the synthesis of active pharmaceutical ingredients containing the (S)-3-aminobutyl side chain (e.g., antidepressants, cardiovascular drugs);

2. Fine chemicals: Used as an organic synthesis building block to construct complex molecules through reactions such as cyano hydrolysis (to form carboxylic acids/amides) and amino alkylation.

Key Physicochemical Properties: 1. Melting Point: 170~174℃ (Crystalline solid, narrow melting point range, can be used as a reference for purity assessment);

2. Solubility: Easily soluble in water, methanol, and ethanol; slightly soluble in ethyl acetate and dichloromethane (the hydrochloride salt is highly polar and has excellent water solubility);

3. Stability: Stable under sealed, dry storage at room temperature; avoid high temperature and humidity (the cyano group is easily hydrolyzed by strong acids/bases, and the amino group is easily oxidized).

Key Quality Indicators: 1. Chiral Purity (ee value): ≥99% (Core indicator, chiral impurities will affect the optical activity of downstream drugs);

2. Chemical Purity (HPLC): ≥98.5%;

3. Moisture Content: ≤0.5% (to avoid deliquescence affecting purity)