Chemical Properties:
Appearance: White to light yellow crystalline powder
Melting point: 38-42℃
Boiling point: 126-128℃ (12mmHg)
Solubility: Soluble in organic solvents such as acetone, dichloromethane, and tetrahydrofuran; sparingly soluble in water.
It belongs to the benzyl bromide class of compounds. The bromomethyl group has high reactivity and readily undergoes nucleophilic substitution reactions, making it an active site for organic synthesis.
Uses:
It is an important pharmaceutical intermediate, a key intermediate in the synthesis of alogliptin benzoate, and can also be used to synthesize other drug molecules.
In organic synthesis, it can also be used as a building block for aromatic ring structures, for the synthesis of other functional organic molecules containing cyano and benzyl groups.