Ethyl 2,5-dibromothiophene-3-carboxylate

China [CN]

Ethyl 2,5-dibromothiophene-3-carboxylatePhysical Properties (referencing similar derivatives):

Appearance: Typically a pale yellow to light brown liquid or crystalline solid.

Solubility: Soluble in non-polar/weakly polar organic solvents such as dichloromethane, ethyl acetate, and toluene; very low solubility in water.

Stability: Relatively stable at room temperature, but easily decomposes upon heating to produce hydrogen bromide; the bromine atom is prone to photochemical reactions, so it should be stored in a cool, dry place, protected from light and air.

Main Uses: As a highly active organic synthesis intermediate, it is widely used in the fields of medicine, pesticides, and functional materials:

Pharmaceutical Research: Used in the synthesis of antibacterial, anti-inflammatory, and antitumor drugs containing a thiophene ring. The bromine atoms at the 2,5-positions can be substituted with amino, thiol, aryl, and other groups to construct biologically active molecular frameworks.

Pesticide Synthesis: Used in the preparation of thiophene-based insecticides and herbicides. The ethyl carboxylate group can be hydrolyzed to a carboxyl group for further modification to improve the targeting of the compound.

Materials Science: Used as a monomer in the synthesis of conductive polymers (such as polythiophene derivatives) for the preparation of organic photovoltaic materials and sensor materials.