1,10-Phenanthrolin-4-ol

China [CN]

Physical Properties (referencing similar derivatives)

Appearance: Typically a pale yellow to orange crystalline powder, the color originating from the light absorption characteristics of the conjugated aromatic heterocycle.

Solubility: Soluble in polar organic solvents such as methanol, ethanol, dimethyl sulfoxide (DMSO), and pyridine, with low solubility in water; it has a high melting point of approximately 240–245℃, is thermally stable but easily decomposes under strong light.

Intramolecular hydrogen bonding contributes to its strong crystallinity and resistance to sublimation.

Main Uses: This compound is a metal ion chelating agent and pharmaceutical intermediate, with core applications including:

Metal ion detection: As a complexing indicator, it can form stable colored complexes with transition metal ions such as Fe²⁺, Cu²⁺, and Zn²⁺, used in water quality monitoring and metal content analysis in ores.

Pharmaceutical research: Its metal complexes exhibit antibacterial and antitumor activity and can be used as lead compounds for the development of new metal-based drugs; it can also be used to synthesize biologically active heterocyclic derivatives.

Materials science: Used in the preparation of luminescent materials and catalytic materials; the coordinated complexes can tune the optical and electrochemical properties of the materials.