Fosaprepitant Dimeglumine(265121-04-8)

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Selling leads
Fosaprepitant Dimeglumine(265121-04-8)
Posting date : Sep 24, 2025
Membership
Free Member Scince Jun 27, 2025
FOB Price
detailed discussion
Min. Order Quantity
1
Supply Abillity
hundreds of kgs
Port
Shanghai Port
Payment Terms
detailed discussion
Package
Convenient package
Keyword :
Category
Contact
Lena
Selling Leads Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
JINLAN
Model Number
+86 15242851296
HS-CODE
-
Package & Delivery Lead Time
Package
Convenient package
Detailed Description

There are three subtypes of neurokinin receptors: NK1, NK2 and NK3. Among them, the NK1 receptor has the strongest binding ability to substance P and the highest content in the vomiting center of the brain. After the NK1 receptor binds to substance P in the central nervous system, it triggers a series of pathophysiological processes such as vomiting, anxiety and migraine. NK1RAChemicalbooks such as apirpitan and fosapirpitan effectively prevent and treat CINV by selectively binding to the NK1 receptor. Usually, acute CINV is related to the activity of the peripheral 5-HT3 energy pathway, while delayed CINV is related to the central P substance. Therefore, compared with 5-HT3RAs, apirpitan and fosapirpitan show obvious advantages for delayed vomiting.


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