Scopine-2,2-dithienyl glycolate

China [CN]

Physical Properties

Appearance: White crystalline solid with fine needle-like shapes.

Melting Point: 173°C.

Chemical Properties: Scopine-2,2-dithienyl glycolate belongs to the dithienyl glycolate family of compounds. Under certain conditions, it exhibits typical properties of esters, including hydrolysis. As an impurity of tiotropium bromide, its chemical structure is somewhat related to tiotropium bromide, requiring control and study during drug synthesis.

Uses: Used as a catalyst in the pharmaceutical industry and can also be used to recover xylene.

Toxicity: Scopine-2,2-dithienyl glycolate, as an intermediate in the synthesis of tiotropium bromide, is highly toxic. As a tertiary amine, it rapidly crosses the blood-brain barrier, exhibits high receptor activity, and is readily absorbed through the skin. This can cause severe anticholinergic symptoms, such as the development of new encephalopathy symptoms after acute poisoning, which have not improved during eight years of follow-up.