2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBONITRILE

China [CN]

Appearance and Condition: Pale yellow to off-white crystalline powder at room temperature, with no noticeable pungent odor. The color is lighter at higher purity levels, while increased impurity content may result in a darker color (e.g., light brown).

Melting Point: Literature reports indicate the melting point of the pure product is approximately 148-152°C (may fluctuate ±2°C due to impurities and requires verification by differential scanning calorimetry (DSC) or capillary chromatography).

Solubility:

Readily soluble in polar organic solvents such as dimethylformamide (DMF), dimethyl sulfoxide (DMSO), acetonitrile, and ethyl acetate;

Soluble in methanol and ethanol (requires ultrasonication or heating to increase solubility; solubility is approximately 5-10 mg/mL at room temperature);

Slightly soluble in chloroform and dichloromethane, and poorly soluble in water and non-polar solvents such as n-hexane and petroleum ether. Stability:

It is stable at room temperature, in a dry place, and protected from light, and is not susceptible to decomposition.

Avoid prolonged contact with strong acids (such as concentrated hydrochloric acid) and strong bases (such as sodium hydroxide): amino groups (-NH₂) may form salts with acids, and cyano groups (-CN) may hydrolyze to carboxyl groups (-COOH) under strong alkaline conditions.

At high temperatures (>200°C), ring structure rearrangement or cyano group decomposition may occur. Avoid prolonged exposure to heat.