2-(Chloromethyl)benzo[b]thiophene

China [CN]

Uses

Pharmaceutical intermediate: Various functional groups can be introduced through chloromethyl substitution reactions, allowing for the synthesis of drug molecules containing a benzothiophene structure, such as certain antibacterial, anti-tumor, or neurological drugs. The aromaticity of the benzothiophene ring and the presence of a sulfur atom enhance the interaction between the molecule and its biological target.

Material intermediate: Used in the preparation of conjugated polymers or organic optoelectronic materials (such as organic solar cell materials and fluorescent probes). The conjugated structure of the benzothiophene backbone can modulate the electronic properties of the material.

Organic building block: Serves as a starting material for the construction of complex heterocyclic compounds, allowing the synthesis of polycyclic thiophene derivatives through cyclization, coupling, and other reactions.

Safety Information

Health Hazards: Chloromethyl is an irritant and potentially toxic, potentially causing irritation to the skin, eyes, and respiratory tract. Immediately rinse with water after inhalation or contact.

Reaction Risks: Reactions with strong nucleophiles (such as amines and sodium alkoxides) may release heat, requiring temperature control. Chlorine atoms may decompose at elevated temperatures to produce toxic gases (such as hydrogen chloride), requiring operation in a fume hood. Storage: Store in a cool, dry place after sealing, away from fire, oxidants and strong alkalis, and out of reach of children.