5,6-diamino-1,10-phenanthroline

China [CN]

Chemical Properties

Coordination Properties: Retaining the strong coordination ability of 1,10-phenanthroline, it can form stable chelates with transition metal ions (such as Fe²⁺, Cu²⁺, and Zn²⁺). The amino group may participate in cooperative coordination or stabilize the complex structure through hydrogen bonding.

Amino Reactivity: The amino group exhibits typical aromatic amine chemical properties, capable of undergoing diazotization, acylation, alkylation, and coupling reactions. This allows for the introduction of other functional groups and expands the molecule's derivatization capabilities.

Oxidative Stability: Relatively stable in air, but strong oxidants may cause oxidation of the amino group or destruction of the ring structure.

Applications

Analytical Chemistry: Utilized as a colorimetric or fluorescent probe for metal ions, its specific coordination with metal ions is used for the detection of metal ions in environmental and biological samples (e.g., spectrophotometry and fluorescence analysis).

Coordination Chemistry Research: Used as a ligand in the synthesis of metal complexes to study their structure, spectral properties, and catalytic activity. Pharmaceutical chemical intermediates: Potentially used in the synthesis of nitrogen-containing heterocyclic drug molecules, utilizing their rigid skeleton and the reactivity of amino groups to construct biologically active molecules.