2-Amino-4,5,6,7-tetrahydro-1,3-benzothiazole

China [CN]

I. Basic Information

Chinese Name: 2-Amino-4,5,6,7-tetrahydro-1,3-benzothiazole

English Name: 2-Amino-4,5,6,7-tetrahydro-1,3-benzothiazole

CAS Number: 1004-32-4

Molecular Formula: C₇H₁₂N₂S

Molecular Weight: 156.25 (Calculated: C 53.81%, H 7.74%, N 17.93%, S 20.52%)

II. Chemical Structure and Characteristics

Structural Analysis: The molecule is based on a 1,3-benzothiazole ring (a benzene ring fused to a thiazole ring, the thiazole ring containing sulfur and nitrogen atoms). However, the benzene ring is fully saturated (with methylene groups at positions 4, 5, 6, and 7 forming a six-membered saturated ring). An amino group (-NH₂) is attached at position 2. Key Features:

The saturated six-membered ring (the original benzene ring) imparts a degree of flexibility to the molecule, making its solubility and reactivity more easily tunable compared to aromatic benzothiazoles.

The sulfur and nitrogen atoms of the thiazole ring have coordination potential, allowing them to bind to metal ions.

The amino group (-NH₂) at position 2 is a strong nucleophilic site, susceptible to reactions such as acylation and alkylation.