Physical and Chemical Properties: Typically solid. Due to the presence of polar carbonyl and acetamide groups in the molecule, it is speculated to have a certain degree of polarity. It is slightly soluble in water and soluble in some polar organic solvents. The melting point may be high, but the specific value is not clearly documented in the literature.
Chemical Reactivity: The amino group on the acetamide group is somewhat nucleophilic and can undergo acylation reactions with acyl chlorides and anhydrides, as well as condensation reactions with aldehydes and ketones. The carbonyl group at position 6 acts as an electrophilic center, allowing addition reactions with nucleophiles, such as Grignard reagents and cyanides. Furthermore, the hydrogen atoms on the thiazole ring may also undergo substitution reactions under certain conditions.