Ethyl 5-chloro-1,3,4-thiadiazole-2-carboxylate

China [CN]

Physical and Chemical Properties

Appearance: Typically solid crystals or powder.

Boiling Point: Approximately 275.2°C (at 760 mmHg).

Density: Approximately 1.498 g/cm³.

Flash Point: Approximately 120.3°C.

Solubility: Soluble in some organic solvents (such as ethanol, ether, and dichloromethane). Specific solubility data should be determined based on actual experimental conditions.

Uses

It is primarily used as an organic synthesis intermediate and is widely used in the synthesis of compounds in pharmaceuticals and pesticides. The thiadiazole ring and ester group in its molecular structure are highly reactive, allowing the construction of more complex functional molecules containing thiadiazole structures through substitution, hydrolysis, and amidation reactions. These can be used, for example, to synthesize compounds with antibacterial and herbicidal biological activities.

Safety: Compared to similar chlorinated heterocyclic compounds and esters, it may be somewhat irritating, potentially to the skin, eyes, and respiratory tract. It is recommended to take appropriate protective measures during handling to avoid direct contact or inhalation. When storing, keep away from strong oxidants, strong acids, strong bases, and other substances and keep the product well ventilated and dry. Please refer to the Material Safety Data Sheet (MSDS) for specific safety information.