exemestane

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exemestane
Posting date : Mar 20, 2019
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Free Member Scince Mar 20, 2019
FOB Price
0.1
Min. Order Quantity
10g
Supply Abillity
10000KG/Month
Port
Shnghai
Payment Terms
CFR
Package
DF
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Place of Origin
China [CN]
Brand Name
Saichaung
HS-CODE
2805-40
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DF
Detailed Description

Product Detailed

  • product name: exemestane
  • cas number: 107868-30-4
  • superlist name: exemestane
  • molecular structure: molecular structure of 107868-30-4 (6-methyleneandrosta-1,4-diene-3,17-dione)
  • formula: c20h24o2

1. aromasin is one of the most powerful estrogen suppressing compounds.

2. aromasin is one of the best compounds to lower the aromatizing effect of steroids.

3. aromasin is available for body builders taking anabolic steroids.

4. it acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen.

5. aromasin is also a kind of .antineoplastic (hormonal) raw materials.

 

 

Description

Aromasin (Exemestane acetate) is one of those weird compounds that nobody really knows what to do with. It's a third generation Aromatase Inhibitor (AI) just like Arimidex and Femerathe third generation aromatase inhibitors, used in the treatment of metastatic breast cancer and used as aid in the treatment of early breast cancer.

 
Function
 
exemestane (trade name aromasin) is a drug used to treat breast cancer. it is a member of the class of drugs known as aromatase inhibitors. some breast cancers require estrogen to grow. those cancers have estrogen receptors (ers), and are called er-positive. they may also be called estrogen-responsive,hormonally-responsive, hormone-receptor-positive. aromatase is an enzyme that synthesizes estrogen. aromatase inhibitors block the synthesis of estrogen. this lowers the estrogen level, and slows the growth of cancers.
 
 
 

Applications

1. exemestane is an oral steroidal aromatase inhibitor that is used in er-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.
 
2. it acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition."
 
3. by being structurally similar to enzyme targets, exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen
 
4.The second generation aromatase inhibitors, used for the treatment of metastatic breast cancer and used as adjuvant therapy for early breast cancer.
5.Pharmaceutical raw materials, is a kind of irreversible steroid body aromatase extinguishing agent, can inhibit the synthesis of estrogen, and reduce circulating estrogen levels, applicable to the progression of disease after treatment with tamoxifen in postmenopausal patients with advanced breast cancer.
 

aromasin is used to fight breast cancer and raise testosterone in the body.

exemestane blocks the process of aromatisation. so it lowers the amount of oestrogen in the body. in early breast cancer, taking exemestane can help to stop breast cancer coming back. in advanced breast cancer the cancer cells may grow more slowly or stop growing completely.

hormones are chemical substances that are produced by glands in the body, which enter the bloodstream and cause effects in other tissues. for example, the hormone testosterone made in the testicles and is responsible for male characteristics such as deepening voice and increased body hair. the use of hormone therapy to treat cancer is based on the observation that receptors for specific hormones that are needed for cell growth are on the surface of some tumor cells. hormone therapies work by stopping the production of a certain hormone, blocking hormone receptors, or substituting chemically similar agents for the active hormone, which cannot be used by the tumor cell. the different types of hormone therapies are categorized by their function and/or the type of hormone that is affected.

 

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