CAS 224785-91-5 Vardenafil

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CAS 224785-91-5 Vardenafil
Posting date : Jan 10, 2018
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Alias: Levitra; Fardenafil,Vardenafil,Vardenafil hydrochlorideMolecular Formula: C23H32N6O4SMolecular Weight:525.06CAS No: 224785-91-5Grade: Pharmaceutical GradeAssay: 98%Appearance: White to almost white crystalline powder Solubility:Soluble in water, ethanolPacking: 1 kg/foil bagUse: It is pharmaceutical raw material, indicated for the treatment of erectile dysfunction
Vardenafil is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to Sildenafil citrate (Viagra) and Tadalafil (Cialis). The difference between the Vardenafil molecule and Sildenafil citrate is that a nitrogen atom has different position and the change of Sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both Sildenafil and Vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than Sildenafil's.
Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with Vardenafil might provoke potentially life-threatening hypotension (low blood pressure).
Further, Vardenafil lengthens QT interval. Therefore it should not be taken by men taking other medications that affect the QT interval (such as Amiodarone). 
 
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