Quick Detail:Frag 176 191
Synonyms: Fragment 177-191, AOD-9604MF: C78H123N23O23S2MW: 1815.08152CAS:221231-10-3Appearance: White PowderPurity: 99%Grade: Pharmaceutical GradeStorage: Closed, below 2 ~ 8 C preservationUsage: AOD9604 actually acts on the reduction of excessive adipose tissues such as increase in muscle mass, and enhances the lipid content of the body.
Description:Fragment (176/191) is a fat loss peptide derived from the GH molecule, which directly initiates lipolysis and inhibits lipogenesis, but in order to better understand this peptide, it is imperative to have at least a rudimentary understanding of its parent hormone .
GH is a polypeptide which contains an amino acid sequence that is 191 amino acids in length. Frag (176191) was developed by isolating and modifying the specific portion of the GH molecule responsible for thehormone's lipolytic and anti-lipogenic effects.
The portion of the molecule responsible for these effects is amino acids 176/191. In every sense, Frag should primarily be considered a fat loss peptide which performs these functions through the same pathways as traditional GH, but without exposing the user to the potentially undesirable side effects which may present themselves during GH administration.
Application : the GH fragment 176-191 stimulates lipolysis and inhibits lipogenesis both en vivo/en vitro.
Fragment 176/191 has shown no effect on growth or insulin resistance, unlike the full GH molecule. This is the newest, most powerful GH fragment on the market. Studies have shown sustained fatloss, aimed directly at adipose tissue.
It has been shown that the fat-reducing effects of GH appear to be controlled by a small analog region of the C-terminus end of the GH molecule. This region consists of amino acids 176/191, thus the name. This peptide fragment works by mimicking the way natural hGH regulates fat metabolism but without the adverse effects on blood sugar that is seen with unmodified hGH.
Growth hormone in sports refers to the use of growth hormones (GH or HGH) for athletic enhancement, as opposed to growth hormone treatment for medical therapy. Lean body massStudies have found that HGH reduces body fat and increases lean body mass. However, no increase in muscle strength was observed. This may be explained by short-term fluid retention. Muscle massResearchers are still debating whether the more noticeable muscles are larger in size as well. It should be clarified, though, that muscle mass is not the same as muscle strength. Some say that human growth hormone will build muscle mass through raised insulin-like growth factors levels leading to heightened protein synthesis without any side effects while other researchers argue that there have been no such findings on young healthy adults. The second argument is more supported by research discoveries that HGH affects muscle protein synthesis no differently than a placebo does.
Growth Hormone peptide fragment 176-191,also known as HGH Frag 176-191 is a modified form of amino acids 176-191 of the GH polypeptide. Investigators at Monash University discovered that the fat-reducing effects of GH appear to be controlled by a small region near one end of the Growth Hormone molecule. This region, which consists of amino acids 176-191, is less than 10% of the total size of the GH molecule and appears to have no effect on growth or insulin resistance. It works by mimicking the way natural Growth Hormone regulates fat metabolism but without the adverse effects on blood sugar or growth that is seen with unmodified Growth Hormone. Like Growth Hormone, the hgH fragment 176-191 stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis (the transformation of nonfat food materials into body fat) both in laboratory testing and in animals and humans.
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