White Crystal Pharmaceutical Intermediates Hydrochloride Procaine HCL for Pain Relief

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White Crystal Pharmaceutical Intermediates Hydrochloride Procaine HCL for Pain R...
Posting date : Mar 25, 2017
Membership
Free Member Scince Mar 24, 2017
FOB Price
$1
Min. Order Quantity
20grams
Supply Abillity
5000KG/week
Port
Guangzhou
Payment Terms
T/T, Bank Transfer, Western Union, Paypal
Package
According to your requirements
Keyword :
Anesthetic
Category
Contact
Tont
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Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
Kafen
HS-CODE
-
Package & Delivery Lead Time
Package
According to your requirements
Delivery Lead Time
Within 12 hours after receiving your payment.
Detailed Description
White Crystal Pharmaceutical Intermediates Hydrochloride Procaine HCL for Pain Relief
Basic Info.
Synonyms: Procaine Hydrochloride; CAS: 51-05-8EINECS: 200-077-2Assay: 99.0-101.0%. Standard: BP/USPPacking: 25kg/cardboard drumCharacter: White crystal to powder, Melting point 154-158, Water solubility soluble. Usage: Active Pharmaceutical Ingredient (API), Local anesthetic for infiltration anesthesia, nerve block, etc. 
Product description: 
Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. It acts mainly by being a sodium channel blocker. Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects. Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques. The routes of administration and concentrations are: For local infiltration use 0.25% to 0.5% (via dilution) and for peripheral nerve blocks use 0.5% (via dilution), 1%, and 2%. (See DOSAGE AND ADMINISTRATION for additional information. )
Application:
Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically . It acts mainly by being a sodium channel blocker. Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.
Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.
Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine LED to the increase of dopamine and serotonin levels in the brain. Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.
Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase, [citation needed] which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.
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