Dapoxetine

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Selling leads
Dapoxetine
Posting date : Mar 19, 2015
Membership
Free Member Scince Mar 16, 2015
FOB Price
negotiable
Min. Order Quantity
10g
Supply Abillity
more than 200kg per month
Port
as require
Payment Terms
T/T,West Union,Money Gram
Package
as requiement or normal package
Keyword :
Category
Contact
Gina Yan
Selling Leads Detail
Company Info
 
Quick Detail
Place of Origin
China [CN]
Brand Name
nanjian
HS-CODE
-
Package & Delivery Lead Time
Package
as requiement or normal package
Delivery Lead Time
3-7 days
Detailed Description
Dapoxetine
Alias: Priligy
English  Synonyms: DAPOXETIN; DAPOXETINE; (S-(+)-N, N-Dimethyl-a-[2-(naphthalenyloxy)ethyl]benzenemethanamine hydrochloride; Dapoxetine hydrochlorideCAS No: 129938-20-1Assay: 98%Molecular Formula: C21H23NO HCLMolecular Weight: 341.88Packing: 1kg/ Foil BagAppearance: White powder, odorless, slightly sweet, soluble in water and alcohol. Can be made into tablets, beverages, wine, capsules and other dosage formsUSES: Treat male premature ejaculation and erectile dysfunction.Applications:Dapoxetine, marketed as Priligy (among and other brands) is the first compound developed specially for the treatment of premature ejaculation (PE) in men 18-64 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant.Treat male premature ejaculation and erectile dysfunction.Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE. Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when dapoxetine is used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.

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