Anastrozole
China [CN] HPLC Injectable Anastrozole Anti Estrogen Steroids / Arimidex Medicine , No Side Effects
Quick Detail:
Arimidex (anastrozole) is the aromatase inhibitor of choice. Arimidex’s mechanism of action — blocking conversion of aromatizable steroids to estrogen — is in contrast to the mechanism of action of anti-estrogens such as clomiphene (Clomid) or tamoxifen (Nolvadex), which block estrogen receptors in some tissues, and activate estrogen receptors in others.
Description:
Anastrozole
Alias: Arimidex
CAS No: 120511-73-1
MF: C17H19N5
MW: 293.37
Purity: 98%
Appearance: white powder.
Applications:
High Purity Anastrozole/Arimidex/CAS No: 120511-73-1
The drug is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to gynecomastia and using moderate amounts of such steroids. Arimidex does not have the side effects of aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much moreso than Cytadren. It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests, or less preferably salivary tests, should be taken after the first week of use to determine if the dosing is correct.
Specifications:
|
Items |
Standard |
Results |
|
Description |
White crystalline powder |
Complies |
|
Identification |
IR HPLC Reactive |
Conform with standard IR Conform with standard HPLC Conform |
|
Solubility |
Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile |
Complies |
|
Total Impurity |
max.0.5% |
0.18% |
|
Total Unspecified Impurity |
max. 0.2% |
0.08% |
|
Individual unspecified impurlty |
max. 0.1% |
0.05% |
|
Related compound B |
max. 0.2% |
0.07% |
|
Related compound C |
max. 0.2% |
0.04% |
|
Related compound D |
max. 0.1% |
0.05% |
|
Related compound E |
max. 0.1% |
0.06% |
|
Limit of cyclohexane |
max. 0.08% |
ND |
|
Limit of ethylacetate |
max. 0.1% |
0.07% |
|
Melting point |
81.0~84.0℃ |
82.5～83.2℃ |
|
Water |
max. 0.3% |
0.21% |
|
Residue on ignition |
max. 0.1% |
0.07% |
|
Heavy Metals |
max.0.001% |
Complies |
|
Assay(HPLC) |
98.0%～102.0% |
99.8% |
|
Storage |
Cool and dry |
|
|
Conclusion |
It complies to USP32 . |
|
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