6-bromo-2-chloro-8-cyclopentyl-5-methyl-pyridine-[2,3-d] pyrimidine-7 (8H) -ketone is used to prepare derivatives of pyridine-[2,3-d] pyrimidine-7 (8H), such as CDK4 and/or CDK6 inhibitors, which can …
N,N,N' -trimethylethylenediamine can be used as an organic synthesis intermediate and a pharmaceutical intermediate, mainly in laboratory research and development processes and chemical and pharmaceut…
This product is used as a reagent to synthesize dihydropyrroquinoline derivatives with anti-cancer activity, and as an EGFR regulator to inhibit L858R/T790M.
AZD9291 is a third-generation oral epidermal growth factor receptor inhibitor (EGFR-TKI) developed by Astrazeneca. Due to its excellent clinical trial results, it was granted accelerated approval by t…
4-fluoro-2-methoxy-5-nitroaniline is a yellow or brown solid at normal temperature and pressure. It has relatively stable chemical properties and does not decompose under normal circumstances. However…
Osimertinib, as a third-generation EGFR inhibitor, is designed to address the unmet market demand for patients with the EGFRT790M mutation. Osimertinib has high selectivity. Its IC50 Chemicalbook valu…
AZD9291(mesylate), also known as osimertinib mesylate, is indicated for the treatment of disease progression that occurred during or after previous treatment with epidermal growth factor receptor (EGF…
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