Bikexostat is an HIV protease inhibitor and has been administered in combination with low-dose ritonavir as a drug enhancer, significantly increasing its plasma concentration.
Bicitravir (BIC) is a second-generation integrated enzyme chain transfer inhibitor (INSTI), which has been approved for fixed-dose combination with entracitabine and tenofovir (Alafenamic Chemical Boo…
Lamivudine is a new type of antiviral drug, belonging to nucleoside reverse transcriptase inhibitors. It has a strong inhibitory effect on hepatitis B virus (HBV) in vitro and in experimentally infect…
Derenavir is a new non-peptide antiretroviral protease inhibitor for the treatment of AIDS. It was first successfully developed by Tibotec, the Icelandic branch of Johnson & Johnson Pharmaceu…
Sofebuvir is a prodrug that can be metabolized into the active antiviral drug 2' -deoxy-2 '-α -fluorine -β -C-methyluridine 5' -monophosphate. Currently, it is in a Phase 3 clinical clinical trial for…
Elbaviragrelvir Tablets are a cutting-edge direct antiviral drug, suitable for the treatment of genotype 1 and genotype 4 hepatitis C. At present, there are approximately 10 million people infected wi…
Grazoprevir anhydrous (MK5172) is an inhibitor of Hepatitis C Virus NS3/4A Protease, and the IC50 values of HCV genotype 1a, 1B and 4 are 7pM, 4pM and 62pM, respectively.
Pibrentasvir (ABT-530) is a novel pan-genotype hepatitis C virus (HCV) NS5A inhibitor, and its EC50 value for HCV replicators containing NS5A genotypes 1 to 6 ranges from 1.4 pM to 5.0 pM.
Gleepvir is an oral RNA polymerase inhibitor that directly acts on the RNA polymerase of the virus, thereby inhibiting the growth and replication of the virus. It is mainly used in the treatment of he…
Entecavir monohydrate is a new type of cyclovaleryl guanosine anti-hepatitis B virus drug. Its pharmacological effect is similar to that of entecavir. Clinically, it is indicated for the treatment of …
Tenofovir alafolamine is a novel nucleotide-type reverse transcriptase inhibitor. After entering liver cells, the drug can be hydrolyzed into tenofovir. Tenofovir is subsequently phosphorylated by int…
Vemlidy (Tenofovir alafolamine fumarate, 25mg, once daily) has been approved by the US FDA for the treatment of chronic hepatitis B virus infection in compensatory liver disease. Vemlidy is an innovat…
Fumaric acid tenofovir is the Gilead listed companies to develop a kind of nucleotide antiviral drugs, in 2001, approved by the FDA for the treatment of human immunodeficiency virus (humanimmunodefici…
vildagliptin is another orally administered dipeptidyl peptidase-IV (DPP-IV) inhibitor following sitagliptin. It was approved for marketing in the European Union in 2008 by Novartis Pharmaceuticals GM…
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